Available Innovations

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BIOTECH & LIFE SCIENCES
DIGITAL
PHYSICAL SCIENCES
AGRICULTURE & FOODTECH

Local Anaesthetic Implants

A novel mode of post-operation pain management in patients, utilising an implant imbued with a non-opioid analgesic.

Contact:

Sandhya Badrinarayanan

CSF-1R inhibitor Discovery Programme

An intuitive approach of using a unique scaffold and structure based approach to synthesis highly potent CSF-1R inhibitors for cancer therapy

Contact:

Sandhya Badrinarayanan

Analogues of Duocarmycin Antibody-Drug Conjugates

Newly synthesised analogues of duocarmycin utilised as an optimised toxic payload in ADCs for cancer treatment.

Contact:

Sandhya Badrinarayanan

Hypoxia-activated DNA-PK inhibitors

Novel DNA-PK inhibitor prodrug which is hypoxia-activated and radiosensitizes tumour cells more potently and specifically, increasing response rate to radiation by blocking the DNA-PK pathway.

Contact:

Sandhya Badrinarayanan

Ester Bond Scaffolding: A New Protein Platform Technology

A novel ‘superglue’ utilising ester bonds to join multiple units together to access many innovative applications.

Contact:

Sandhya Badrinarayanan

Tumour Targeted Irreversible FGFR inhibitors

A targeted approach to deliver potent irreversible FGFR inhibitors utilising hypoxia selective activation for cancer therapy.

Contact:

Sandhya Badrinarayanan

Rheumatic Fever Diagnostic Tool

A new Streptococcal serological test to enable efficient and reliable diagnosis of rheumatic fever and post-streptococcal glomerulonephritis.

Contact:

Sandhya Badrinarayanan

Culicinin D: Novel Antibody-Drug Conjugates

A new class of toxic payload for antibody-drug conjugates to inhibit cancer growth by ATP synthase inhibition.

Contact:

Sandhya Badrinarayanan

Real-time 3D Heart Mapping for Atrial Fibrillation

A heart mapping system that will improve cardiac ablation procedures in patients with persistent or permanent atrial fibrillation. By enabling real time 3D mapping of electrical activity in the heart, the technology provides a unique way of constructing maps that will reduce treatment times and improve outcomes of ablation procedures.

Contact:

Kent Lee

Pressure vessel for sensor recalibration

A pressure measuring system is proposed where the drift of a pressure sensor can be quantified by detecting changes in compliance of a pressure vessel which encloses the sensor.

Contact:

Kent Lee

Erp44/Adiponectin

A novel cell penetrating peptide derived from the ERp44 binding region of adiponectin and Immunoglobulin (IgM) was synthesised and conjugated with cell penetrating sequences. These peptides were designed to modulate in vivo oligomeric composition and secretion of the insulin-sensitizing high-molecular-weight (HMW) isoform of adiponectin. Targeting ERp44-adiponectin interactions with short peptides represents an effective method to treat obesity related metabolic disorders.

Contact:

Sandhya Badrinarayanan

 

Click here to view a complete list of Biomedical and MedTech Innovations

 

 

Micro-CV

A new method for finding translational shifts with sub-pixel accuracy, which can be combined with a novel method to perform accurate multi-camera calibration to create a hand-held device to measure surface 3D deformation, and 3D strain map.

Contact:

Stephen Flint

Organ Emulation On FPGA

Emulated organs built from sophisticated software and Field-Programmable Gate Arrays, mimicking human organ behaviour from the cell level, including disease states, with unprecedented accuracy - personalized to individuals - in real time

Contact:

Joe Rouse

Tinnitus and Sound Intensive Video Game

Simple auditory games that are customised to the individual’s condition. The four training applications work to exercise and improve sound categorisation, discrimination and localisation. In the games, correct navigation is directed through auditory cues – responding to “good” sounds is positively rewarded, and responding to “bad” sounds is negatively rewarded. The listening tasks become progressively harder as the game continues. Over time, players are trained to not hear their tinnitus. Initial tests have shown significant auditory improvement

Contact:

Kent Lee

Psychoacoustic technology for hearing loss

Development of a demonstrable technology which compensates excessive frequency masking in hearing loss to improve and speech intelligibility in a crowded room and enhance vocal clarity in musical entertainment

Contact:

Kent Lee

Antimicrobial Aniline Copolymers

Aniline copolymers and the synthesis thereof for use as antimicrobial (antibacterial, antifungal or antiviral material) material of for the manufacture of antimicrobial objects, suitable for use in the health, food, packaging, water, paint, wood, textile, poultry, glass, paper, rubber, ceramic, seafood, sports, plastic and agricultural industries.

Contact:

Stephen Flint

Fire-retardant Polypropylene

A non-halogenated fire retardant polypropylene (NH-FRPP) developed through an innovative new process to obtain UL 94-V-0 fire rating without any detrimental effect on mechanical properties.

Contact:

Stephen Flint

Optrode

An all-fibre spectroscopic fluorescence bacterial detection system that requires minimal manual intervention, and can give accurate results on site within 30 minutes. Results can show a quantification of bacterial load, live dead ratios for use in antibiotic resistance tests and in the future, species identification.

Contact:

Stephen Flint

Mass Spectrometer - Portable dynamic time-of-flight

A novel time-of-flight mass spectrometer based on UniServices patented technology which promises to differentiate performance for analysis of high masses, particularly suited for the growing field of proteomics.

Contact:

Stephen Flint

Grasp Enhancing Four-Output Differential for Soft Exogloves and Prosthetics

A compact, robust, and energy efficient differential system for splitting force from one electric motor across four outputs. Designed to increased the actuation and grasping of soft exoglove systems while reducing cost and compexity.

Contact:

Sam Wilkins

Timber Grading System (using Laser Vibrometer)

Utilising laser power to determine the properties of materials such as the ripeness of fruit or the quality of timber non-destructively, in-line and in real time.

Contact:

Stephen Flint

Equine embryo-derived stem cells

The use of equine stem cells and derivatives in equine regenerative medicine focusing especially but not exclusively on tendon injury.

Contact:

Kent Lee